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In a 16-week multiple ascending dose (MAD) trial, participants treated with high doses of Petrelintide experienced an average weight loss of 8.6%, while the placebo group saw only a 1.7% reduction

Figure 5 Overall, these results show that a 3-month clinical intervention of L-GSH supplementation in individuals with T2DM resulted in significantly increased levels of IFN-, TNF-, IL-2, and decreased levels of IL-10 when compared to before L-GSH supplementation

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Inhibition of dipeptidyl peptidase-4 impairs ventricular function and promotes cardiac fibrosis in high fat-fed diabetic mice